Tumor involves 1 or both ovaries with pelvic extension below the pelvic brim. Epithelial ovarian cancer generally presents at an advanced stage and is the most common cause of gynaecological cancer death. Ovarian cancer is a disease laden with paradigms, and it is a serious health problem. Incorporation of pazopanib in maintenance therapy of ovarian cancer. In 20, it is estimated that there will be 22240 new cases of ovarian cancer and 14030 ovarian cancer deaths in the united states us alone. Populationbased screening has been ineffective, but new approaches for early diagnosis and prevention that leverage molecular genomics are in development. The disease typically presents in postmenopausal women, with a few months of abdominal pain and distension.
The reason for the high death rate is the late presentation in most cases, meaning that the disease is widely metastatic within the abdomen. Epithelial ovarian cancer is the fourth commonest cause of female cancer death in the developed world. Panorama global globocan 2012 iarc section of cancer information 54 2014 4. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext.150 53 1546 1420 639 222 828 742 208 52 794 1038 147 541 1201 1023 598 214 606 1559 1296 1083 1389 299 1103 517 668 479 326 692 302 651 944 1249 232 826 18 1253 582